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Home »Detabase » Lactabase » Beta Lactamase » Classification » Molecular » Class D

Class D Beta- Lactamases

This class includes:

OXA (oxacillinase)

The OXA group of β-lactamases mainly occur in Acinetobacter species and are divided into two clusters. OXA carbapenemases hydrolyse carbapenems very slowly in vitro, and the high MICs seen for some Acinetobacter hosts (>64 mg/L) may reflect secondary mechanisms. They are sometimes augmented in clinical isolates by additional resistance mechanisms, such as impermeability or efflux