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Home »Detabase » Lactabase » Beta Lactamase » Beta Lactam Antibiotics » Betalacteasme Inhibitors » Tazobactam

Tazobactam

Tazobactam is a compound which inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin or Zosyn. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.

Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.

Tazobactam

Fig: Tazobactam